Wound repair is a complex process involving an orchestrated series of events involving blood clotting, removal of dead cells, production of new tissue and revascularization.
By understanding the cellular and molecular mechanisms involved in wound healing, researchers aim to develop therapies that facilitate repair and enhance the regenerative capacity of tissues to reduce scarring and dysfunction. Researchers study different approaches to enhance regeneration, including implanting stem cells and scaffolds to support restoration of tissue architecture, applying molecules that attract cells to wounds, controlling inflammation and protecting against infection.
PCOM researchers dissect the events leading to normal and abnormal wound healing and tissue regeneration in the brain, eyes, heart and kidneys. Their goal is to develop novel approaches to protect undamaged cells, restore homeostasis, reduce scarring and prevent distortions in tissue architecture.
PCOM biomedical sciences professor Lindon Young, PhD, was awarded a patent for an injectable solution he invented that can prevent tissue damage in the heart.
PCOM aims to develop innovative approaches to promoting health through basic, translational, clinical, behavioral, education and community research projects.
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