Wound Healing and Tissue Regeneration
Research at PCOM
Restoration of normal architecture and function following acute and chronic injury
is a complex and self-limiting process involving recruitment of cells that clear dead
tissue and facilitate wound healing, the differentiation of stem and progenitor cells,
and in some organs such as the liver, activation and proliferation of mature cells.
Impaired tissue regeneration that occurs in diseases such as diabetes may lead to
the deposition of fibrotic tissue that impedes function.
PCOM researchers dissect the events leading to normal and abnormal wound healing and
tissue regeneration in the liver, skin, heart, nervous system and eyes, with the purpose
of developing treatments that promote the restoration of function.