Inflammation, Allergy and Autoimmunity

Rapid and specific activation of subpopulations of cells of the immune system is critical for combating infection and promoting tissue repair. Suppression of immune responses is required for preventing rejection of transplanted organs and reducing inflammation. Aberrant and chronic immune responses may result in or exacerbate autoimmune diseases, tissue destruction and life threatening allergic reactions.

PCOM researchers study the molecular mechanisms regulating immune responses with the purpose of identifying novel approaches to preventing and slowing the progression of hyper immune mediated disorders. PCOM faculty also participate in several clinical trials designed to assess the effects of immunosuppressant drugs following organ transplantation and the onset of diabetes.