Precision Medicine Research

NIH All of Us Program

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NIH All of Us Research Program 
Precision Medicine Research at PCOM

Through a relationship with the National Institutes of Health (NIH), students and faculty at PCOM's three locations are eligible to participate in ongoing studies and develop their own research projects with the All of Us Research Program.

PCOM researchers will have access to an expansive cohort dataset and unique tools through the NIH Research Hub in this Precision Medicine Initiative. Winston Price, MD, FACPE, associate professor of pediatrics and director of pathway programs, is coordinating PCOM's access to these research tools.

About the All of Us Research Program

The All of Us Research Program is a program, under the direction of NIH Director, Dr. Francis Collins, that was launched in 2017 with the mission to enroll one million or more people from across the U.S. to share information about their health, habits and lifestyle. By looking for patterns, researchers may learn more about what affects people’s health.

The program has already enrolled more than 387,000 participants and covers a diverse and inclusive population. This important effort helps to assure that the data repository contains information from every sector of our population: young and old; sick and well; urban and rural; LGTBQ and straight; physically challenged, blind, deaf; and every racial and ethnic group. By having the weight of numbers and diversity the program can hope to find the answers to improving our population's health and well-being.

Tools for PCOM Researchers

All of Us Research Hub

The All of Us Research Hub is a gateway to the participant data.

Researcher Workbench platform

The Research Hub also houses the Researcher Workbench and its suite of custom tools. The Workbench offers access to additional levels of data, workspaces, a cohort builder and an interactive notebook environment.

These tools are available to registered and approved PCOM All of Us researchers subsequent to the Vanderbilt University Medical Center Agreement executed by Kenneth Veit, DO '76, MBA, provost, senior vice president of academic affairs and dean.

About the All of Us Data Platform

Research support through the All of Us platform

All of Us is a broad program that can support research on many aspects of health, not just a single medical or biological research question. The data platform enables research that can:

  • Increase wellness and resilience and promote healthy living.
  • Reduce health disparities and improve health equity in populations that are historically underrepresented in biomedical research (UBR).
  • Develop improved risk assessment and prevention strategies to preempt disease.
  • Provide earlier and more accurate diagnosis to decrease illness burden.
  • Improve health outcomes and reduce disease impact through improved treatment and development of precision interventions.
Access tiers

All of Us offers two different access tiers: One for the general public and a second, restricted tier for registered researchers.

Benefits for researchers

Researchers have opportunities to:

  • Save time and resources and accelerate research breakthroughs by accessing:
    • a rich data resource, including biospecimens and increasingly robust electronic health records.
    • a longitudinal dataset that will follow participants as they move, age, develop relationships, get sick and try treatments.
    • a diverse cohort of participants.
    • raw data and data that are already cleaned and curated.
    • robust computing and analytic tools to support complex data analyses in a secure data environment.
    • a group of engaged participants who may be interested in participating in ancillary studies.
  • Share workspaces and analyses with research partners and reviewers
    Learn from the program’s pilots and experiments.
  • Leverage innovations of other studies and cohorts.

PCOM Strategic Plan

The plan for the NIH All of Us program for PCOM researchers will be in alignment with PCOM's 2025 strategic plan and the 5-year initiatives of the PCOM research team across all campuses:

  • Increase the opportunity to build robust research projects for new and seasoned PCOM researchers.
  • Increase PCOM researchers input to the NIH Precision Medicine solutions to improving health outcomes.
  • Encourage the PCOM community to assist in recruitment of All of Us participants from family, friends and people in the surrounding PCOM campus communities and nationwide.
  • Expand opportunities for young researchers to present abstracts, obtain grants and publish articles in peer reviewed journals.
  • Establish a framework for mentorship of young researchers.

Contact

Students and faculty interested in participating in All of Us research opportunities should contact Dr. Winston Price at winstonpr@pcom.edu.

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