Skeletal Muscle Development, Function and Disease
Proper coupling of neurons, skeletal muscle fibers and intracellular filamentous contractile
proteins is essential for voluntary movements.
PCOM faculty are engaged in research that defines the mechanisms regulating skeletal
muscle formation and contraction. Other studies focus on the effects of inherited
genetic abnormalities and mechanical ventilation that lead to muscle weakness and
atrophy, with the goal of developing compensatory approaches to treat myopathies.