Digest Magazine – Who Tells the Story of Health?

This issue of Digest Magazine brings together voices from across the PCOM community—alumni, faculty, staff and students—to explore how health and medicine are communicated, interpreted and understood in an increasingly complex media environment.
Digest, the magazine for alumni and friends of Philadelphia College of Osteopathic Medicine, is published by the Office of Marketing and Communications.
The magazine reports on osteopathic and other professional trends of interest to alumni of the College’s doctoral and graduate programs at PCOM, PCOM Georgia and PCOM South Georgia.
Have a Story Idea?
Email your story idea to Jennifer Schaffer Leone, editor of Digest Magazine, at jenniferleo@pcom.edu.
Office Hours: With Dr. Matthew L. Holt
From Injection to Innovation: The Next Chapter in GLP-1 Therapy

By Gabrielle DePietro
Matthew L. Holt, PharmD, BCPS, is an assistant professor of pharmacology at PCOM South Georgia with experience in ambulatory care and chronic disease management.
Prior to joining PCOM South Georgia, he served as a clinical ambulatory care pharmacist at the Piedmont Columbus Family Medicine Center, where he worked closely with patients managing type 2 diabetes. That experience has positioned him as a knowledgeable voice on GLP-1 medications and the evolving landscape of weight-loss therapies.
In discussing the new oral Wegovy option, Dr. Holt noted that while the risks and side effects are essentially the same as injectable versions, the pill may offer a practical advantage because it leaves the body more quickly and may appeal to patients hesitant about needles.
Looking ahead, Dr. Holt believes the oral option could broaden access to GLP-1 therapy and shape future weight-loss medications.
“As new players enter the space, each will aim to stand out—whether by offering simpler dosing instructions, more convenient administration, or more affordable pricing options,” he said. “We’ll likely see more prescriptions across the U.S. in the months to come.”
Second Opinion
Quick Takes
Credits
VOL. 87, NO. 2, USPS, 413-060
Digest Magazine is produced by the Office of Marketing and Communications under the direction of Wendy W. Romano, chief marketing and communications officer.
EDITOR
Jennifer Schaffer Leone, MA
PUBLICATION DESIGN
Abigail Harmon
CONTRIBUTORS
Gabrielle DePietro
Janice Fisher
Kristen Hopf
Brandon Lausch
Jennifer Schaffer Leone
Alexis Martina
Meghan McCall
Joy Williford
ILLUSTRATION
Diego Abreu
PHOTOGRAPHY
Bruce Fairfield
William Griffith
Melissa Kelly
Michelle Lynn
Anthony Stalcup
Questions or comments: pcomcommunications@pcom.edu
Class Notes or address changes: alumni@pcom.edu
Periodical postage is paid at Upper Darby, PA, and at additional mailing offices.
Opinions expressed are not necessarily shared by the College or the editor.
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