Student Research Spotlight October 12, 2020
Hilary Gray (DO '22)
Hilary Gray (DO ’22) received her undergraduate degree in 2015 from Hamilton College
in Clinton, New York, where she majored in Biology and minored in Hispanic Studies.
From there, she completed a one-year post-baccalaureate program at Cornell University
in Ithaca, New York. Currently, Ms. Gray is a third-year medical student at Philadelphia College of Osteopathic Medicine (PCOM).
Below, Ms. Gray shares her experience researching data in hopes of aiding physicians
in their efforts to recognize and provide care for pediatric patients who’ve been
exposed to phenylcyclohexyl piperidine (PCP).
What are you studying?
Currently I am working on a research project aimed at understanding patterns in how
PCP intoxication occurs in young children and specific signs and symptoms these pediatric
patients display. While not a common cause of toxicity in young children in the U.S.,
when it does occur, PCP intoxication puts young children at risk for serious injury.
Current literature gives only a vague understanding of how children under the age
of 5 become intoxicated with PCP and what clinicians should look for when evaluating
a pediatric patient that indicate PCP toxicity.
What prompted you to pursue research?
During the didactic years of medical school, I yearned for more direct engagement with clinical medicine. While I appreciated
the material I was learning, I most enjoyed any opportunities I had to experience
clinical medicine first-hand. Along with activities through the Emergency Medicine
Club at PCOM, clinical research was another means for me to engage with current medical practice. When it comes to
research in toxicology specifically, I find pharmacology fascinating, but also challenging
to cement, especially as a first- and second-year student when we are not yet spending
our days on the wards. Interacting with pharmacology from a research perspective further
helps me to build my knowledge base - knowledge that I will utilize regularly in my
desired residency which is emergency medicine.
Please provide a synopsis of your research experience.
I began working with Dr. Osterhoudt at the Poison Control Center at Children’s Hospital
of Philadelphia in the summer of 2019 after completing my first year at PCOM. After
treating a young patient who spent multiple days in intensive care due to consequences
of PCP intoxication earlier that year, Dr. Osterhoudt recognized pediatric PCP intoxication
as an area ripe for research. We worked to obtain data from multiple Poison Control
Centers across the country, constructed an original means of coding the information,
and translated and analyzed the data via a combination of in-person meetings, telephone
calls and email communication throughout my 2019-2020 school year. This past May,
we virtually presented a poster of our research at the Pediatric Academic Societies
meeting. Most recently, we had the opportunity to present our research via virtual
poster at the North American Congress of Clinical Toxicology (NACCT) Conference this
past September. During the conference, I was awarded the 2020 AACT Student and Trainee
NACCT Travel Award by the American Academy of Clinical Toxicology for my work.
What are your responsibilities in this research project?
I was responsible for identifying which case records from the American Association
of Poison Control Centers’ (AAPCC) National Poison Data System fell within our inclusion
criteria, and then translating the findings from the case records into numerical data
that could be analyzed. I worked with Dr. Osterhoudt to then perform statistical analysis
of our data and formulate our findings. Because our data came from multi-state case
records, these records needed to be individually examined to determine if they were
in fact a case of PCP intoxication, and if they fit within our research criteria,
and then to examine what actually occurred in these cases. Different states code and
format their records slightly differently, and sometimes not accurately, and thus
each record needed to be read in its entirety to ensure its inclusion in our study
was warranted. We then worked together to formulate our abstract. Currently, we are
working on our full paper for publication.
What is the broader impact of your research?
Our findings contribute to a greater understanding of the etiologies responsible for
pediatric PCP intoxication and an updated depiction of the clinical presentation of
such toxicity in young children.
In addition to the project described here, Ms. Gray also previously conducted clinical
research at the Lankenau Institute for Medical Research in Wynnewood, Pennsylvania
and at Wills Eye Hospital (Philadelphia, PA) during her post-baccalaureate program.
Additionally, Ms. Gray worked as a Patient Care Associate on a medical/surgical floor
at Einstein Medical Center (Philadelphia, PA) prior to PCOM.
Learn more about research at PCOM and read about other student research highlights.
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About Philadelphia College of Osteopathic Medicine
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