Dr. Michael McGuinness joined the faculty of PCOM as an assistant professor of anatomy
in 1999, teaching gross anatomy and histology. In 2005, he received the Lindback Foundation
Award for distinguished teaching. In 2007, he became a course director for the gross
anatomy section of Structural Principles of Osteopathic Medicine (SPOM) and continues
to teach in both the gross anatomy and histology sections of that course. In 2012,
he helped develop and became co-director of Human Gross Anatomy, a summer course taught
to physicians assistants and physical therapists.
As a supervisor of graduate and undergraduate research, he has trained several students
in microscopy, confocal microscopy, cellular and molecular biology techniques. Dr.
McGuinness served as a postdoctoral research associate at the R.W. Johnson Pharmaceutical
Research Institute from 1997 to 1999, where he began the first detailed study of estrogen
response in Sertoli and Leydig cells. This research generated valuable information
for the use of estrogenic compounds to treat osteoporosis, cardiovascular disease,
cancer and infertility. Ongoing research continues to focuses on the effects of estrogens
on cell interaction in the testis. More recently, Dr. McGuinness has maintained interest
in how steroids affect physiology, but has switched focus to study how estrogens influence
the interaction between monocytes and endothelial cells and their role in inflammation.