Department of Bio-Medical Sciences - Philadelphia
Professor of Clinical Pharmacology

Frederick J. Goldstein, PhD, FCP


Office: 215-871-6859
Research Page

Dr. Goldstein is Professor of Clinical Pharmacology in the Department of Bio-Medical Sciences at PCOM, and serves as Coordinator of Pharmacology. His research interests focus on adding non-opioid drugs to improve analgesia in patients who have chronic pain.

In addition to his teaching and research at PCOM, he lectures in pharmacology at the University of Pennsylvania School of Dental Medicine.

Dr. Goldstein serves on the editorial board of, and reviews submissions for, the Journal of Opioid Management.

He is an active member of the National Board of Osteopathic Medical Examiners where he writes and reviews questions for the COMLEX Level 1 test.

  • Education

    PhD, Pharmacology, University of the Sciences in Philadelphia, 1968
    MSc, Pharmacology, University of the Sciences in Philadelphia, 1965
    BSc, University of the Sciences in Philadelphia, 1963

  • Research

    Research Keywords:

    Pain Management
    Opioid Analgesia
    Osteopathic Manipulative Treatment (OMT)

  • Awards

    Lindback Award for Distinguished Teaching from the USP in 1990.

  • Publications

    Selected Publications

    Goldstein, F.J., "Opioids, Medical Education and CDC Guidelines" Journal of Family Medicine and Community Health, June 2016.

    Hoegerl C., Goldstein, F.J., Sartorius J. “Evaluation of a Stroke Alert Program in the Emergency Dept; A Pilot Study” JAOA 111 21-27(2011).

    Goldstein, F.J., Jeck, S., Nicholas, A., Berman, M.A. Lerario, M, "Preoperative Morphine with Postoperative Osteopathic Manipulative Treatment Reduces Patient Analgesic Use After Hysterectomy" JAOA 105 273-279 (2005).

    McPhilemy, J.J., Hudanich, R., Hoertz, M., Goldstein, F.J., and Salinsky, J.P., "Osteochondral Autograft Transfer for the Treatment of large Chondral Defects and Osteochondritis Dessicans of the Knee: A Functional Outcome Study" JAmer Osteo Acad of Orthopedics37 62-65 (2000).

    Selected Presentations

    “Pain Management for Chronic Pain Patients”, Compassion and Care National Organization, Philadelphia Meeting, 2014

    “Pain Treatment For Your Loved Ones” [Presentation for the lay public], Abington Presbyterain Church & Beth Sholom Synagogue, 2014

    “Clinical Research: Development of an Investigation” Resident Orientation, PCOM, 2014.

  • Memberships

    Dr. Goldstein's memberships include the Rho Chi Honor Society, Sigma Xi, American Society for Pharmacology and Experimental Therapeutics, American College of Clinical Pharmacology, American Pain Society, and International Association for the Study of Pain.

  • Grants

    "Pennsylvania Study of Chronic Obstructive Pulmonary Exacerbations (PA-SCOPE) Phase 2: Impact of Easy Access to Preventive Care for Impending Acute COPD Exacerbation" Funded by a Pennsylvania Department of Health research grant from the state's share of the national tobacco settlement; Temple University School of Medicine, designated as a Center of Excellence, served as the lead institution.

    "Effect of Pre-operative Morphine and Post-op OMT Upon Post-op Pain After Total Abdominal Hysterectomy or Myomectomy." Principal investigator: Goldstein, F.J. Co-Investigators: Berman, M.A., Jeck, S., and Nicholas, A. Funded by the American Osteopathic Association

    "Evaluation of the Effect of Selected Osteopathic Manipulative Techniques on Headache Pain: A Randomized Clinical Outcomes Study." Funded by both the American Osteopathic Association and National Headache Foundation