2nd Annual AlzPI and PCOM Symposium Advances Dialogue on Infection-Linked Brain Disorders
October 14, 2025
Researchers, clinicians, patients and advocates from around the world gathered last
week at Ohio University for the 2nd Annual AlzPI and PCOM Symposium, the one-day hybrid
event aimed at sharing interdisciplinary research on the role of infections and the
microbiome—in Alzheimer's disease, related dementias, and other neurological and psychiatric
diseases.
The annual conference highlighted emerging evidence connecting infection and inflammation
to neurodegeneration and called for stronger collaboration across researchers in neurology,
psychiatry, immunology, microbiology and infectious disease.
More than 20 experts presented research exploring how microbial and immune factors
contribute to disorders such as Alzheimer's disease, Parkinson's disease, PANDAS/PANS,
Lyme disease, long COVID and multiple sclerosis. Among the speakers was Brian Balin, PhD, Director of the Center for Chronic Disorders of Aging at PCOM, who discussed his three decades of research on microbial involvement in Alzheimer's
disease.
Other speakers included patients and caregivers, including Nikki Schultek, Co-Founder and Executive Director of AlzPI and Founding Director of the PCOM Pathobiome Research Center, who emphasized patient-centered collaboration, alongside others sharing personal
stories that underscored the human impact of infection-associated brain disorders.
“This year's meeting reaffirmed a growing consensus—that understanding infection-associated
brain disorders requires not just advanced science, but empathy, collaboration and
the courage to reimagine the framework of how brain health itself is evaluated and
maintained,” shared Schultek when reflecting on the day’s successes.
The symposium closed with a unifying call to dismantle disciplinary silos and adopt
a shared biological lens across neurological and psychiatric disease. Both Dr. Balin
and Schultek are confident that meetings such as these will continue to foster connection
and collaboration, ultimately creating more patient-accessible therapies.
About Philadelphia College of Osteopathic Medicine
Established in 1899, Philadelphia College of Osteopathic Medicine (PCOM) has trained
thousands of highly competent, caring physicians, health practitioners and behavioral
scientists who practice a “whole person” approach to care—treating people, not just
symptoms. PCOM, a private, not-for-profit accredited institution of higher education,
operates three campuses (PCOM, PCOM Georgia and PCOM South Georgia) and offers doctoral degrees in clinical psychology, educational psychology, osteopathic
medicine, pharmacy, physical therapy, and school psychology. The college also offers
graduate degrees in applied behavior analysis, applied positive psychology, biomedical
sciences, forensic medicine, medical laboratory science, mental health counseling,
physician assistant studies, and school psychology. PCOM students learn the importance
of health promotion, research, education and service to the community. Through its
community-based Healthcare Centers, PCOM provides care to medically underserved populations.
For more information, visit pcom.edu or call 215-871-6100.
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Gabrielle DePietro Associate Director, News and Media Relations Office of Marketing and Communications Email:gabrielde2@pcom.edu Office:215-871-6304