LORI REDMOND, PHD 
Professor of Anatomy and Neuroscience

Research

The incidence of intellectual disability is 1-3% in the human population (NIH/NLM) and the number of autistic individuals is on the rise. A shared pathology in human and mouse models of intellectual disability, neurodegenerative diseases, and other neurological disorders is abnormal cerebral cortical organization and neuronal morphology. The research in Dr. Redmond’s lab examines the roles of proteins and genes in the development and maturation of the cerebral cortex. The role of signaling proteins, such as CaMKIIβ, that translate neuronal activity into changes in neuronal shape and connections is the focus of Dr. Redmond’s research. Genetically modified mice, immunohistochemical, biochemical, and molecular biological approaches are used to elucidate the role of signaling proteins in the development of the central nervous system and differentiation of neurons.

Grants

PI: Lori R Hardy, PhD
CCDA Pilot grant
CaMKIIβ regulation of the actin cytoskeleton
Direct costs: $9,000
07/01/12-06/30/13

PI: Lori R Hardy, PhD
1 R01 NS046809
Calcium signaling in neuronal differentiation
Direct costs: $971,250
03/01/04 – 08/31/10

PI: Lori R Hardy, PhD
IGP PSRP
CaMKIIβ in neuronal development
Direct costs: $25,000
10/01/09 - 09/30/10

PI: Robert K. Yu
CoInv: Lori R Hardy, PhD; and several others
5T32NS045543-04
Neurodegenerative diseases and neural repair
Direct costs: Funding for 1 predoctoral and 3 postdoctoral trainees
01/07/05 – 06/30/10