Xinyu (Eric) Wang, PhD | PCOM Georgia Faculty
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XINYU (ERIC) WANG, PHD
Associate Professor

Dr. Wang received his Bachelor of Science degree in Pharmacy from the School of Pharmaceutical Sciences at Peking University in Beijing, China. He earned his PhD in pharmaceutics from the University of Texas at Austin followed by postdoctoral training at the U.S. Army Institute of Surgical Research at San Antonio, Texas.

Dr. Wang joined PCOM School of Pharmacy in 2010 right before the start of its inaugural class. As a founding member, he is mainly involved in teaching pharmaceutics related courses including Biopharmaceutics, Pharmacokinetics, Pharmaceutical Compounding, and Pharmaceutical Calculation. He devoted himself to the development of an effective and rigorous curriculum and focused on improving student learning outcome. He also mentors PharmD and Biomed Thesis students in research projects and guides them to present their research outcome at local and national scientific meetings. His effort in teaching is highly appreciated by PharmD students who chose him as Teacher of the Year in 2014.

Dr. Eric Wang’s research interest is focused on the drug discovery and development to identify potential candidates with anti-cancer, anti-inflammatory, and anti-oxidant properties. He recently explored the inhibitory effects of compounds derived from natural sources on multiple myeloma, a plasma cell cancer characterized by the accumulation of malignant cells in bone marrow. His effort in multiple myeloma research was recognized, and he was recently named a 2016 American Association of Colleges of Pharmacy (AACP) New Investigator Award recipient. He has presented his research in various national and international conferences and published peer-reviewed articles in different pharmaceutical fields including medicinal chemistry, molecular pharmacology, pharmaceutical analysis, and pharmacokinetics.

Dr. Wang has served on many committees including curriculum, assessment, admissions, scholarship and awards, faculty development, faculty search, academic appeal, diversity and ACPE self-study. He participated in the ACPE accreditation process and contributed to the success of School of Pharmacy accreditation in 2014 and site visit in 2016.

Education

  • PhD in Pharmaceutical Sciences, University of Texas at Austin, Austin, Texas, 2008
  • BS in Pharmacy, Peking University Health Science Center, Beijing, China, 1997

Training

  • BRB-ArrayTools Data Analysis Workshop, NIH, Washington DC, July14, 2006
  • Pharmacokinetic/Pharmacodynamic Modeling workshop; School of Pharmacy & Pharmaceutical Sciences, University at Buffalo, Buffalo, New York; May 18-21, 2008
  • Introductory Compounding Lab Training, PCCA, Houston, Texas; June 8-9, 2015

Grants

Role: Principal Investigator
Award type: External funding from pharmaceutical industry
Funding Agency: Aurinia Pharmaceuticals
Title: Comparing the Effects of Voclosporin, Cyclosporin A and Tacrolimus on Calcineurin Isoform Activity and Mediators of Fibrosis in Kidney Cells In Vitro
Duration: 08/1/2021-07/30/2023

Role: Co-Principal Investigator
Award type: The Community-Based Research Faculty Fellowship
Funding Agency: PCOM Alumni Association
Title: Impact of Implementing Medication Therapy Management Service for Underserved Populations Children with Disabilities
Duration: 03/2022 - 02/2023

Role: Principal Investigator
Award type: Internal funding for MS-Thesis of Biomed students
Funding Agency: PCOM Division of Research 
Title: Preparation of xanthohumol (XN)-incorporated iron oxide nanoparticles and their inhibitory effects on multiple myeloma cell growth
Duration: 07/1/2021-06/30/2022

Role: Principal Investigator
Award type: Internal funding for MS-Thesis of Biomed students
Funding Agency: PCOM Division of Research 
Title: Preparation of caffeic acid phenethyl ester (CAPE)-incorporated nanoparticles and their inhibitory effects on multiple myeloma cell growth
Duration: 07/1/2020-06/30/2021

Role: Principal Investigator
Award type: Internal funding for MS-Thesis of Biomed students
Funding Agency: PCOM Division of Research
Title: Anti-myeloma effect of xanthohumol, a prenylated flavonoid from hops plant
Duration: 07/1/2019-06/30/2020

Role: Principal Investigator
Award type: Internal funding
Funding Agency: PCOM Division of Research
Title: Preparation of caffeic acid phenethyl ester (CAPE)-incorporated nanoparticles and their inhibitory effects on multiple myeloma cell growth
Duration: 07/1/2019-06/30/2020

Role: Principal Investigator
Award type: Internal funding for MS-Thesis of Biomed students
Funding Agency: PCOM Division of Research
Title: Anti-myeloma effect and structure activity relationship of caffeic acid phenethyl ester on multiple myeloma
Duration: 07/1/2018-06/30/2019

Role: Principal Investigator
Award type: Internal funding for MS-Thesis of Biomed students
Funding Agency: PCOM Chief Research and Scientific Officer (CRSO)-funding
Title: Anti-myeloma effect of imidazole and methyl derivatives of a synthetic oleanane triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO)
Duration: 07/1/2017-06/30/2018

Role: Principal Investigator
Award type: Internal funding for MS-Thesis of Biomed students
Funding Agency: PCOM Chief Research and Scientific Officer (CRSO)-funding
Title: Effects of caffeic acid phenethyl ester (CAPE) and its derivatives on human hepatic cancer cells
Duration: 07/1/2017-06/30/2018

Role: Principal Investigator
Award type: New Investigator Award
Funding source: American Association of Colleges of Pharmacy
Title: Anti-Myeloma Effect of Caffeic Acid Phenethyl Ester: The Role of Oxidative Stress
Duration: 1/1/2016-12/31/2016

Role: Principal Investigator
Award type: Internal funding for MS-Thesis of Biomed students
Funding Agency: PCOM Chief Research and Scientific Officer (CRSO)-funding
Title: Anti-Myeloma Effect of a Novel Derivative of Caffeic Acid Phenethyl Ester (FCAPE)
Duration: 07/1/2016-06/30/2017

Role: Principal investigator
Award type: Internal funding
Funding Agency: PCOM CSO-funding
Title: Attenuation of immune-complex mediated inflammation through inhibition of NF-κB activation by caffeic acid phenethyl ester (CAPE)
Duration: 12/17/2013-11/30/2015

Role: Principal investigator
Award type: Internal funding
Funding Agency: PCOM Center for Chronic Disorders of Aging (CCDA)-funding
Title: Inhibitory effects of caffeic acid phenethyl ester on multiple myeloma cell growth: Nrf2 and NF-κB crosstalk
Duration: 08/01/2013-07/30/2014

Role: Principal investigator
Award type: Internal funding
Funding Agency: PCOM CCDA-funding
Title: Inhibitory effects of caffeic acid phenethyl ester on multiple myeloma cell growth
Duration: 08/01/2012-07/30/2013

Role: Principal investigator
Award type: Internal funding
Funding Agency: PCOM CCDA-funding
Title: Identification of potential drug candidates for ameliorating oxidative stress involved ischemia reperfusion injury
Duration: 08/01/2011-07/30/2012

Courses

Biopharmaceutics
Pharmacokinetics
Pharmaceutics
Pharmaceutics Compounding Lab
Pharmaceutical Calculations

Research

Dr. Eric Wang’s research interest is focused on the drug discovery and development to identify potential drug candidates with anti-cancer, anti-inflammatory, and anti-oxidant properties. Currently, he is investigating the effects of potential drug candidates from natural sources for the treatment of multiple myeloma, a cancer of plasma cells in the bone marrow. This disease remains incurable and results in 10 to 15 % of blood cancer and 20% human death related to blood and bone marrow cancer. His research is funded through PCOM intramural grants and supported by American Association of Colleges of Pharmacy (AACP) as he is the recipient of AACP New Investigator Award 2016. He has presented his research in various national and international conferences and published peer-reviewed articles in different pharmaceutical fields including medicinal chemistry, molecular pharmacology, pharmaceutical analysis and pharmacokinetics.

Awards

  • 2023 Teacher of the Year, PCOM School of Pharmacy
  • 2022 Teacher of the Year, PCOM School of Pharmacy
  • 2020-2021 Teacher of the Year, PCOM School of Pharmacy
  • 2019 Teacher of the Year, PCOM School of Pharmacy
  • 2019 Advisor of the Year, Student Organization Council at PCOM
  • AACP New Investigator Award, 2016
  • 2014 Teacher of the Year, PCOM School of Pharmacy
  • 2013 Peach Teaching Award, PCOM School of Pharmacy
  • 2012 Peach Teaching Award, PCOM School of Pharmacy
  • Sigma Xi, the Scientific Research Society
  • Phi Kappa Phi honor society
  • Rho Chi honor society in pharmacy

PCOM Student Mentee Awards
  • 2023: Excellence in Research Award - PCOM Georgia, Evaluating the effects of novel calcineurin inhibitor Voclosporin on calcineurin isoform activity and nephrotoxicity in comparison to cyclosporine and tacrolimus. Tu Dang, Janice Tong, Teresa Collins, Robert Huizinga, Handong Ma, Srujana Rayalam, Shashidharamurthy Taval, Mindy George-Weinstein, Xinyu Wang.
  • 2021: Division of Research Award for Excellence in Research - PCOM Georgia, Preparation of Caffeic Acid Phenethyl Ester-Incorporated Nanoparticles And Their Inhibitory Effects On Multiple Myeloma Cell Growth. Barkley Smith, Yuancheng Li, Travis Fields, Michael Tucker, Hui Mao, Xinyu (Eric) Wang.
  • 2021: Pharmacy Department Award for Excellence in Research, Anti-Myeloma Effect of Xanthohumol On Multiple Myeloma Cells. Michael Tucker, Erica Wong, Srujana Rayalam, Xinyu (Eric) Wang
  • 2020: AACP Walmart Scholar: Jonathan Park, AACP Walmart Scholar Mentor: Dr. Xinyu (Eric) Wang
  • 2018: PCOM Research Day PharmD student poster, Second Place. Inhibitory Effect of Resveratrol and its Derivative Pinostilbene on Multiple Myeloma Cell Growth.Jonathan Park, Jay Mehta, Jang Hee Cho, Deborah Adedeji, Xinyu (Eric) Wang.
  • 2017: PCOM Research Day PharmD student poster, First place. Anti-myeloma effect of imidazole and methyl derivatives of a synthetic oleanane triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO). Teena John, Elizabeth Hernandez Martin, Jonathan Park, Jay Mehta, Xinyu (Eric) Wang.
  • 2017: PCOM Research Day Biomed Thesis student poster, Honorable mentioning. Anti-Cancer Effect of Fluorinated Caffeic Acid Phenethyl Ester (FCAPE) on Human Multiple Myeloma Cells. Elizabeth Hernandez Martin and Xinyu (Eric) Wang.
  • 2016: PCOM Research Day PharmD student poster, Second place. Inhibitory effect of caffeic acid phenethyl ester (CAPE) on human multiple myeloma cell growth: the role of oxidative stress. Yesung Ban, Jung-jung Shang, Xinyu (Eric) Wang.
  • 2014: PCOM Research Day PharmD student poster, First place. Inhibitory effect of caffeic acid phenethyl ester (CAPE) on human multiple myeloma cell growth: induction of apoptosis and stress / toxicity pathway. Hana Paek, Marie Bozman, Xinyu (Eric) Wang.
  • 2013: PCOM Research Day PharmD student poster, First place. Cytotoxicity of caffeic acid phenethyl ester (CAPE) in human multiple myeloma cells: the involvement of oxidative stress and inflammatory response. Marie Bozman, Xinyu (Eric) Wang.

Memberships

American Association of Pharmaceutical Scientists
American Association of Advancement of Science
American Association of Colleges of Pharmacy
American Society for Pharmacology and Experimental Therapeutics
International Society for the Study of Xenobiotics

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