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SRUJANA RAYALAM, PHD
Department of Pharmaceutical Sciences
Associate Professor


Srujana Rayalam

Contact

Email: srujanara@pcom.edu
Office: 6784077358
Publications and Selected Works

Dr. Rayalam is the recipient of the first ‘Virbac Animal Health - Soloxine Award’ for her work on feline thyrotropin during her doctoral program and is a Morris Animal Foundation Fellow. Before joining PCOM, Dr. Rayalam worked as a research faculty in the Dept. of Animal and Dairy Science at the University of Georgia. Her major research interests are in the fields of obesity, post-menopausal osteoporosis and phytochemicals. Dr. Rayalam has authored/co-authored over 30 articles published in peer-reviewed journals and contributed several chapters to the text/reference books for DVM and graduate students. Her work on phytochemicals and obesity is patented and has been cited in several magazines including Women’s World.

Teaching has always been a passion for Dr. Rayalam. She primarily teaches physiology and pathophysiology to first-year PharmD students and is also involved in teaching multiple courses across the PharmD curriculum.

  • Education

    • BVSc&AH (DVM equivalent): S.V.Veterinary University, A.P, India
    • Master’s in Veterinary Science: S.V.Veterinary University, A.P, India
    • PhD (Pharmacology): University of Georgia, Athens, GA
  • Courses

    • Physiology and Pathophysiology I and II
    • Immunology and Microbiology
    • Integrated Therapeutics IV
    • Anatomy Lab
  • Research

    Dr. Rayalam has worked in the areas of obesity, body weight regulation, phytochemicals and adipocyte biochemistry for over 8 years. Her research interests include:

    1) to study the adipocyte life cycle and to understand the interaction of adipocytes with other cell types as an approach to address several problems associated with obesity;

    2) to develop novel treatment strategies for obesity by inducing transdifferentiation of white to beige adipocytes and to inhibit lipid accumulation in white adipocytes; and

    3) to identify combinations of phytochemicals and vitamins that have synergistic anti-adipogenic effects with an ultimate goal of developing pharmaceuticals or nutraceuticals for prevention and treatment of obesity and associated disorders. Aging is accompanied by an accumulation of adipocytes in bone marrow and Dr. Rayalam's other interest is to understand the fat-bone interaction and to identify molecular targets for the prevention of weight gain and bone loss associated with aging. Dr. Rayalam collaborates with UGA to develop novel therapies for obesity and osteoporosis.

  • Awards

    • Teacher of the Year 2018, PCOM School of Pharmacy
    • Teacher of the Year 2016, PCOM School of Pharmacy
    • Educator of Excellence - Champions of Healthcare – PCOM GA Campus, 2015
    • Teacher of the Year 2015, PCOM School of Pharmacy
    • Peach Award, 2013 (In recognition of outstanding performance and commitment to teaching at PCOM, School of Pharmacy)
    • Virbac Animal Health - Soloxine Award, 2005 for achievement in excellence of endocrinology
    • Graduate Student Travel Award, 2005
    • Morris Animal Foundation Fellow, 2002
    • Veterinary Medical Experiment Station Fellowship, University of Georgia, 2002-‘03
    • Indian Association of Lady Veterinarians-Chapter Book Prize, 2001
  • Grants

    Title: Vitamin D and Phytochemicals for Prevention of Obesity and Osteoporosis (2012) 
    Funding source: PCOM Center for Chronic Disorders of Aging (CCDA)
    Role: Principal Investigator
    Funding Amount: $9,600
    Status: complete

    Title: Phytochemicals induce transdifferentiation of white to brown like adipocytes (2012)
    Funding source: Chief Science Officer Internal Funding, PCOM
    Role: Principal Investigator
    Funding Amount: $16,500
    Status: complete

    Title: Anti-obesity, anti-inflammatory and pro-osteogenic effects of phytochemicals plus vitamin D in post-menopausal rat model (2014)
    Funding source: Chief Science Officer Internal Funding, PCOM
    Role: Principal Investigator
    Funding Amount: $9,600
    Status: complete

    Title: The search for compounds that stimulate thermogenesis and induce transdifferentiation of white to beige adipocytes (2014) 
    Funding source: Chief Science Officer Internal Funding, PCOM
    Role: Principal Investigator
    Funding Amount: $8,600
    Status: complete

    Title: Synergistic effects of phytochemicals and immunomodulatory glycans LNFPIII on the beiging of adipocytes: a novel therapeutic approach for obesity (2016)
    Funding source: PCOM Center for Chronic Disorders of Aging (CCDA)
    Role: Principal Investigator
    Funding Amount: $9,600
    Status: complete

    Title: Role of AMPK pathway in xanthohumol induced anti-obesity effects (2016)
    Funding source: CSRO internal funding
    Role: Principal Investigator
    Funding Amount: $13,000
    Status: complete

    Title: Synergistic anti-obesity effects of immunomodulatory glycans and phytochemicals (2017)
    Funding source: CSRO internal funding
    Role: Principal Investigator
    Funding Amount: $10,000
    Status: On going

  • Other

    Patents
    • Xanthohumol Compositions and Methods of Using Same. Inventors: Clifton A. Baile, Mary Anne Della-Fera, Jeong-Yeh Yang, Srujana Rayalam, Hea Jin Park; United States Patent: 8,101,213 (Jan 24, 2012)
    • Compositions and methods of the treatment of obesity and osteoporosis; Inventors: Mary Anne Della-Fera, Srujana Rayalam, Clifton A. Baile, USPTO Application #:20100093678 - Class: 514167 (USPTO)

    Adhoc Reviewer
    • Journal of Nutritional Biochemistry
    • PLOS One
    • Nutrients
    • Journal of animal science and biotechnology
    • Lipids in health and disease
    • Biochimie
    • Physiological Research
    • Phytomedicine

    Service on Grant Review Panels
    • National Institute of Food and Agriculture's (NIFA) Exploratory Research program

    Invited Speaker
    • Novel molecular targets for prevention and treatment of obesity and osteoporosis, 5th International Congress on Nutrition and Cancer, Sep 9-11, 2012, Elazig, Turkey
    • Browning of white fat: a therapeutic tool for metabolic disorders, Georgia Pharmacy Convention; Amelia Island, FL June 17 2017

    Genbank Submissions
    • Ferguson, D.C., Rayalam, S., Eizenstat, L.D., Hoenig, M.E. Feline thyrotropin alpha subunit, complete cds. Accession number# AY972823
    • Ferguson, D.C., Eizenstat, L.D., Rayalam, S., Hoenig, M.E. Feline thyrotropin beta subunit. Accession number# AY972824
  • Memberships

    • The Obesity Society
    • The Endocrine Society
    • American Society for Nutrition
    • American Veterinary Medical Association
    • American Association for the Advancement of Science