Investigators are required to conduct literature searches for alternatives to animal use based on the Three Rs approach.

PCOM IACUC: Literature Search Requirements for Use of Animals in Research

Useful Keywords for Alternatives Seaches

AWIC Tips for Searching for Alternatives to Animal Research and Testing

Center for Animal Alternatives, University of California - Davis

ALTBIB - NLM's alternatives to animal testing database on the web

Alternatives in Education Resources from the USDA

AltWeb Worksheet Essentials

Mesh for Alternatives Searching

"Retrieval Approaches for Information on Alternative Methods to Animal Experiments," Report and Recommendations of the International Workshop,Berlin in 2003, Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments