Shashidharamurthy Taval, PhD | PCOM Georgia Faculty
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SHASHIDHARAMURTHY TAVAL, PHD
Associate Professor

678-407-7373

Affiliations

Adjunct Faculty at Department of Pathology, Emory University, Atlanta, GA. USA.

Dr. Shashidharamurthy's initial interest in teaching started during his training towards obtaining a PhD degree. Upon entering the PhD program, the most influential of his mentors were those who successfully achieved a career by combining teaching with research. As a graduate student, Dr. Shashidharamurthy learned to appreciate the aspects of teaching and research that an academic career could provide. In addition to teaching, he has also been involved in mentoring and supervising many work-study students, research assistants and postdoctoral fellows.

Education

  • PhD, Department of Biochemistry, University of Mysore, India, 2004
  • MS, Department of Biochemistry, University of Mysore, India, 1996
  • BS, University of Mysore, India, 1994

Courses

At PCOM-SOP, Dr. Shashidharamurthy involved in teaching the following courses to Doctor of Pharmacy students.

  • PHAR 224G Immunology and Microbiology (coordinator)
  • PHAR 150G Biochemistry
  • PHAR 351G Toxicology
  • PHAR 312G Integrated Therapeutics

Research

One of the major focuses of Dr. Shashidharamurthy's research is to delineate the molecular mechanism(s) lipocalin-2 (Lcn2) during various autoimmune/inflammatory disorders such as arthritis and lupus. This may eventually lead to development of novel therapeutic approaches. More recently his research has shown that Lcn2 plays a protective role during the pathogenesis of immune-complex mediated arthritis (Arthritis Rheum. 2013;65:1064-73). The preliminary data suggests that Lcn2 knockout mice are defective in the production of anti-inflammatory cytokines and T reg expansion during arthritis condition. These results demonstrate that Lcn2 is a host-protective factor against systemic autoimmune disease.

Apart from this project, our laboratory is also focused on: The individual role of FcGamma receptor and complement proteins during the pathogenesis of immune-complex (IC) mediated vasculitis (funded by American Heart Association), Attenuation of IC-mediated inflammation by prostaglandin E2 receptor antagonists and Synergistic effect of IC’s and TLR ligands during IC-mediated inflammatory disorders.

Grants

Role: Principal Investigator
Award type: Scientist Development Grant Program
Funding source: American Heart Association
Title: Blocking of immune-complex mediated vasculitis using recombinant Fc receptors.
Duration: 1/1/2011-12/31/2015

Role: Principal Investigator
Award type: Internal funding
Funding Agency: (Chief Scientific officer) CSO-funding
Title: Synergistic effect of immune-complex and TLR ligand during immune-complex mediated disorders.
Duration: 12/1/2012-12/31/2013

Role: Principal Investigator
Award type: Internal funding
Funding Agency: CSO-funding for MS-Thesis
Title: Attenuation of antibody- mediated inflammation by prostaglandin E2 receptor antagonists during autoimmune arthritis.
Duration: 08/1/2012-08/31/2014

Role: Co Principle investigator
Award type: Internal funding
Funding Agency: CSO-funding
Title: Attenuation of immune-complex mediated inflammation through inhibition of NFkb activation by caffeic acid phenethyl ester (CAPE).
Duration: 12/17/2013-11/30/2015

Awards

  • Early Career Faculty Award from American Association of Immunologist (2013-2015)
  • American Association of Immunologist Trainee Awards. 2011 (two awards for two different presentations)
  • Scientist Development grant program Award from America Heart Association. 2011

Memberships

  • American Association of Immunologist. 2005- present
  • American College of Clinical Pharmacy (ACCP). 2012- present
  • American Association for the Advancement of Science. 2005-2010

Editorial Service

  1. Biochimie 2004- present
  2. Comparative Biochemistry and physiology, 2004- present
  3. Planta Medica, 2006- present
  4. Nutrition Journal, 2007- present
  5. Current Medicinal Chemistry, 2008- present
  6. Immunopharmacology And Immunotoxicology, 2008- present
  7. Archives of Biochemistry and Biophysics, 2009- present
  8. Bioorganic & Medicinal Chemistry Letters, 2010- present
  9. European Journal of Cancer 2013- present
  10. Clinical and Applied Thrombosis/Hemostasis 2013- present
  11. Cellular Physiology and Biochemistry, 2014- present
  12. Plose One, 2015- present

Grant Review Study Section Member

Serving as active committee member on American Heart Association Grant review committee under Vascular Endothelial Biology and Function - Basic Science and Immunology and Virology - Basic Science study sections

Invited Speaker at National/International Conferences

Renowned speaker and Chairing the session (Track:5 Allergy) at 4th international conference on Clinical and Experimental Dermatology too be held at San Antonio, Texas, USA. April 14-16, 2014.

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