Department of Bio-Medical Sciences - Philadelphia
Professor of Anatomy

Michael P. McGuinness, PhD


Email: michaelmcg@pcom.edu
Office: 215-871-6524
Research Page

Dr. Michael McGuinness joined the faculty of PCOM as an Assistant Professor of Anatomy in 1999, teaching gross anatomy and histology. In 2005, he received the Lindback Foundation Award for distinguished teaching. In 2007, he became a Course Director for the gross anatomy section of Structural Principles of Osteopathic Medicine and continues to teach in both the gross anatomy and histology sections of that course. In 2012, he helped develop and became Co-director of Human Gross Anatomy, a summer course taught to Physicians Assistants and Physical Therapists.

As a supervisor of graduate and undergraduate research, he has trained several students in microscopy, confocal microscopy, cellular and molecular biology techniques. Dr. McGuinness served as a postdoctoral research associate at the R.W. Johnson Pharmaceutical Research Institute from 1997 to 1999, where he began the first detailed study of estrogen response in Sertoli and Leydig cells. This research generated valuable information for the use of estrogenic compounds to treat osteoporosis, cardiovascular disease, cancer and infertility. Ongoing research continues to focuses on the effects of estrogens on cell interaction in the testis. More recently, Dr. McGuinness has maintained interest in how steroids affect physiology, but has switched focus to study how estrogens influence the interaction between monocytes and endothelial cells and their role in inflammation.

  • Research

    Research Keywords

    Reproductive Biology

  • Awards

    2009, 2011, 2012 – PCOM Basic Science Professor of the Year Award

    2005 – Christian R and Mary F. Lindback Award for Distinguished Teaching

  • Publications

    Selected Presentation

    Functional Estrogen Receptors in the Nucleus and Plasma Membrane of TM3 Leydig Cell Line. (2010) American Society of Physiology. FASEB meeting, Anaheim, CA

  • Other


    2011-2014: PCOM Relay for Life
    2008-2014: PCOM Pediatrics’ Club Talent Auction


    2012-3014: Course Director, Human Gross Anatomy (Summer Term)
    2007 -2014: Course Director, Structural Principles of Osteopathic Medicine
    2007-2011: Course Director, Structural Principles of Osteopathic Medicine Summer Remedial Course
    2009-2014: Executive Secretary, Humanity Gifts Registry
    2011-2012: President, PCOM chapter, Sigma Xi
    2010-2013: Chair, Academic Appeals Committee
    2006-2007: Chair, Faculty Senate