Department of Bio-Medical Sciences - Philadelphia
Professor of Biochemistry and Molecular Biology

Farzaneh Daghigh, PhD


Email: farzanehd@pcom.edu
Office: 215-871-6449
Research Page

Dr. Farzaneh Daghigh has served as a course director for the gastroenterological sciences course in the DO curriculum. She lectures on biochemistry, metabolism, and nutrition to the students in the DO and the Biomedical master programs.

  • Education

    Postdoctoral fellow - DuPont-Merck Pharmaceutical

    Temple University School of Medicine
    Department of Biochemistry
    Ph.D. Biochemistry

    The College of New Jersey
    B.S. Chemistry, summa cum laude

  • Courses

    Dr. Daghigh participates in the following courses:

    First Year DO class: Teach in CMBM and Cardiovascular Diseases courses
    Second Year DO: Gastroenterology Course Director; Teach in Life Stages course
    Biomed program: Teach in MBM course

  • Research

    Dr. Daghigh’s current research projects:

    Project 1
    Examine the possibility of dietary ω-3 fatty acids, found in fish oil or oily fish, in diminishing chronic inflammation in human lung fibroblast (HLF) by reducing nitric oxide. DHA and EPA, ω-3 fatty acids have anti-inflammatory actions that may benefit asthmatic patients health. Data recently presented at the Pauling Institute, May 2013.

    Project 2
    The Nutri One on One Project. The goal of this research study is to improve patient’s health at the neighboring PCOM clinics. This project is focused to positively alter patients' knowledge, attitudes, and behaviors about basic nutrition through one on one coaching in the PCOM affiliated medical clinics. This study was presented at the Experimental Biology, 2014.

    Research keywords:

    Nitric oxide
    Arginine metabolism
    Nutritional education
    Nutritional intervention

  • Publications

    Selected Publications

    Jennifer King, Jeffrey E. Harris, David Kuo, and Farzaneh Daghigh, One-on-One: The Assessment and Evaluation of a Brief One-on-One Nutritional Coaching in Patients Affected by Metabolic Syndrome. Journal of Biomedical Education, Volume 2015 (2015), Article ID 580287.

    Farzaneh Daghigh, Ph.D., David Vettori, DO, and Jeffrey Harris, Ph.D. (2011). Nutrition in Medical Education: History, Current Status, and Resources. Topics in Clinical Nutrition 26(2) Spring 2011 issue

    Book Chapter: (2007) Oxidative Stress: Clinical and Biomedical Implications, Chapter 18, Reactive Oxidant Species and Emerging Therapies in Clinical Medicine. Nova Publishers.

    Farzaneh Daghigh, Ph.D., Ruth C. Borghaei, Ph.D., Ruth Thornton, Ph.D., and Joseph H. Bee, BS. (2002). Human Gingival Fibroblasts produce nitric oxide in response to pro-inflammatory cytokines. J. Periodontology. Apr;73 (4):392-400.

    Selected Presentations

    “To Veg or not to Veg”, was the topic of a presentation at the Philadelphia Science Festival in May 2014. This was a review of the current literature and the state of biomedical consequences of Vegetarianism and Western diets.

    Nutri One-on-One: Improving patients’ Metabolic Profile with One-on-One Nutritional Coaching. Jennifer King, MS, Jeffrey E. Harris, D.P.H., M.P.H., R.D., David Kuo, DO, Farzaneh Daghigh, Ph.D., The Experimental Biology Convention, May 2014. San Diego, CA.

    Vamsee Duggirala, Donald Hasenmeyer, and Farzaneh Daghigh (2013). Effect of Nicotine and Omega-3 Polyunsatated Fatty acids on Arginine Metabolism in Asthma. The Linus Pauling Institute Conference, “Diet and Optimum Health”. May, 2013, Corvallis, Oregon.

  • Grants

    June 2008-June 2009: Principal Investigator, one year grant for $10,000 funded by CCDA (the center for Chronic Disease of Aging). This project is titled, “Determination of the physiologically and pathophysiologicaly relevance of arginase isoforms in NO production by human gingival fibroblasts”.

    2007-2008: Co-Principal Investigator of AOA Grant # 07-10-557 “Documenting Mechanics and Mechanisms in Pedal Pump OMT” for $22,712.

    2006-2007: Co-Principal Investigator of a grant from the Korman’s Foundation for $400,000 titled “Pilot: Gait Analysis, Balance, Nitric Oxide, Fluid Distribution, and Quality-of-Life of Patients with Parkinson’s Disease (PD) treated with Whole Body, Periodic Acceleration or Osteopathic Manipulative Treatment (OMT)”.

    October 2003: Co-Principal Investigator of a grant from the Karen and Herbert Lotman Foundation for $25,000 titled “A pilot study to establish a protocol to determine the change in nitric oxide (NO) concentrations after treatment with the Accelerated Therapeutic 101 (AT101) table in normal healthy subjects and patient volunteers”.

    Media Dr. Daghigh discussed the costs and benefits of a vegetarian diet. The Philadelphia Inquirer, Nov. 9, 2014

    Dr. Daghigh discussed the health ramifications of a vegetarian diet at Franklin Institute's program "To Veg or Not to Veg.", May 30, 2014

    Dr. Daghigh Weighs in on Diet Cookies, Farzaneh Daghigh, PhD, professor, biochemistry/molecular biology, was tapped by Channel Six to weigh in on the ingredients of a popular diet cookie. Video on PCOM’s Facebook page, October 7, 2009