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  Academic Programs

Huo Lu, PhD

Huo Lu, PhD

Associate Professor of Anatomy

Contact
Ph: 678-225-7469
FX: 678-225-7479
E-mail: huolu@pcom.edu

Education

PhD, Pennsylvania State University College of Medicine, Hershey PA, 1998
MS, Shanghai University of Traditional Chinese Medicine Shanghai Qigong Institute, 1989
MD, Nanjing University of Traditional Chinese Medicine, 1986

Narrative

Dr. Lu earned a MD degree from the University of Nanjing Traditional Chinese Medicine and a MS in Physiology from the University of Shanghai Traditional Chinese Medicine. Dr. Lu attended graduate school at the Pennsylvania State University College of Medicine and earned his PhD in Anatomy. In April 1994, he was recognized by the Pennsylvania State University College of Medicine Class of 1997 for Excellence in Teaching. Dr. Lu then went to the California Institute of Technology to continue postdoctoral studies in cerebellar research using in vitro, in vivo and computational modeling methods. He received a NIMH Postdoctoral Fellowship, National Research Service Award (NRSA) Training Grant. After moving to the Research Imaging Center, UTHSCSA, his research expanded to imaging studies using MRI techniques. He was also involved in teaching graduate and medical students to do basic science. He was then promoted to research assistant professor. He is now teaching Gross Anatomy, Histology and Neuroscience for the osteopathic medical students at GA-PCOM. He also teaches Experimental Design and Data Analysis in Biomedical Science Program. He has established a lab capable of doing both in vivo and in vitro studies of cerebellar function in GA campus. Meanwhile, he is conducting collaborative research as an Adjunct Associate Professor in the Department of Biology at Emory University using electrophysiological and optogenetic methods. This research was supported by CCDA and NIH grants. Dr. Lu is married. His hobby is playing badminton.

Honors/Awards/Grants

Fellowship for visiting scholar, Ministry of Education in China (2000-2001)

NIMH Postdoctoral Fellowship, National Research Service Award (NRSA) Training Grant (1999-2002)

Pilot research for “Optogenetic Study of Cerebellar Circuit”, PCOM CCDA (2010-2011)

NINDS Award for the research “Optogenetic investigation of olivary inputs to the deep cerebellar nuclei” (R21, 1R21NS074296), Co-Investigator, (2011-2013)

Pilot research for "Study Cerebellar Nuclei Output to Thalamus Using Autopatch Recording", PCOM CCDA (2014-2015)

Selected Publications

Lu, H. and Larson-Prior, L.J. (1996) Serotonergic Modulation of Evoked Responses in Turtle Cerebellar Purkinje Cells. J. Neurophysiol. 76(5):3102-3113.

Lu, H., Prior, F.W. and Larson-Prior, L.J. (1997) Information processing in a cerebellar granule cell. In:Computational Neuroscience: Trends in Research ‘1997. J. Bower (Ed.), Plenum Press.

Lu, H., Prior, F.W. and Larson-Prior, L.J. (1998) The role of feedforward and feedback inhibition on frequency-dependent information processing in a cerebellar granule cell. In: Computational Neuroscience: Trends in Research ‘1998. J. Bower (Ed.), Plenum Press.

Lu, H., Hartmann, M. and Bower, J.M. (2005) Correlations between Purkinje Cell Unit Activity and Granule Cell Layer Field Potentials: An in vivo Extracellular Study. J. Neurophysil. 94: 1849 - 1860.

Luo, Q., Liu, H., Parris, B., Lu, H., Senseman, D.M., Gao, J. (2007) Modeling Oxygen Effects in Tissue Preparation Neuronal Current MRI. Magnetic Resonance in Medicine. 58:407–412.

Lu, H., Esquivel, A.V. Bower, J.M. (2009) 3-D electron microscopic reconstruction of segments of rat cerebellar Purkinje cell dendrites receiving ascending and parallel fiber granule cell synaptic inputs. J. Comparative Neurology. 514(6):583-94.

Luo, Q., Lu, H., Lu, H., Yang, Y., Senseman, D., Worsley, K., Gao, J. (2009) Physiologically Evoked Neuronal Current MRI in a Bloodless Turtle Brain: Detectable or Not? Neuroimage. 47(4):1268-76.

Luo, Q., Lu, H., Lu, H., Yang, Y., Gao, J. (2010) Comparison of visually evoked local field potentials in isolated turtle brain:Patterned versus blank stimulation. Journal of Neuroscience Methods. 187:26–32.

Lu, H., Yang, B., Jaeger, D.J. Responses in Cerebellar Nuclei Neurons to Olivary Input using Channelrhodopsin-2 Stimulation in Transgenic Mice: in vivo and in vitro studies. in preparation

Selected Presentations

Signal Processing in a Cerebellar Granule Cell Biomedical Engineering Society 1996 Annual Fall Meeting Penn State University, University Park, PA, October 1996

Serotonergic Modulation of Frequency-Dependent Information Processing in the Cerebellum Department of Neuroscience and Anatomy, Milton S. Hershey Medical Center, Hershey, PA, January 1997

Noradrenergic Modulation in the Cerebellar Cortex: from in vitro to in computo Chinese Conference on Biomedical Engineering 1999 Southeast University Nanjing, November 1999

What modulates the activity of neurons? Research Imaging Center, UTHSCSA, San Antonio, April 2002 Cerebellar Plasticity: For the Sake of Motor Learning or Metabolic Modulation? Research Imaging Center, UTHSCSA, San Antonio, November 2005

Spontaneous and Evoked Activities in the Cerebellar Cortex: in vivo Extracellular Recordings Using Rats Neuroimaging Research Branch, National Institute on Drug Abuse, NIH Baltimore, November 2007

 

Last Updated: 4/17/15