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Goldstein, Frederick

Frederick J Goldstein, PhD, FCP

Frederick J. Goldstein, PhD, FCP

Professor of Clinical Pharmacology
Department of Bio-Medical Sciences

Ph: 215-871-6859
FX: 215-871-6889
E-mail: fredg@pcom.edu


PhD, Pharmacology, University of the Sciences in Philadelphia, 1968
MSc, Pharmacology, University of the Sciences in Philadelphia, 1965
BSc, University of the Sciences in Philadelphia, 1963


Dr. Goldstein is Professor of Clinical Pharmacology, Department of Bio-Medical Sciences, at PCOM; he joined the faculty in 1993. Prior to that time he served on the staff of USP. At PCOM he serves as Coordinator of Pharmacology for the medical school. In this capacity he has an extensive level of teaching in the First, Second and Third years of this curriculum, covering many topics in neuropharmacology (e.g., antidepressants, narcotic analgesics, drugs of abuse {e.g., LSD}). Dr. Goldstein also lectures in the PCOM Graduate Program in Biomedical Sciences. In addition, he also gives some presentations in Pharmacology at the University of Pennsylvania School of Dental Medicine.

Dr. Goldstein performs clinical investigations to reduce pain in post-operative patients and for those with chronic pain. He currently conducts a pharmacology research study in hospice patients to improve their analgesia.

Within the Graduate Medical Education department, he serves as Director of the Clinical Master of Science Program, and Director of Research. He oversees the annual awarding of grants from the PCOM MEDNet to osteopathic residents who wish to conduct clinical investigations.

He is a Fellow in Clinical Pharmacology (FCP) of the American College of Clinical Pharmacology.

Dr. Goldstein serves on the Editorial Boards of the Journal of Clinical Pharmacology, Journal of the American Osteopathic Association, and Journal of Opioid Management; he reviews papers for these publications. In 2008, he also began to review papers for the Osteopathic Medicine and Primary Care Journal.

He served as Book Review Editor for the Journal of the American Osteopathic Association from 2007 to 2012. His memberships include the Rho Chi Honor Society, Sigma Xi, American Society for Pharmacology and Experimental Therapeutics, American College of Clinical Pharmacology, American Pain Society, and International Association for the Study of Pain.

Dr. Goldstein received his Ph.D. in Pharmacology from the Philadelphia College of Pharmacy and Science (now known as the University of the Sciences in Philadelphia).


Lindback Award for Distinguished Teaching from the USP in 1990.

Selected Publications

Peer-reviewed Journals

Hoegerl C., Goldstein, F.J., Sartorius J. “Evaluation of a Stroke Alert Program in the Emergency Dept; A Pilot Study” JAOA 111 21-27(2011).

Goldstein, F.J., Jeck, S., Nicholas, A., Berman, M.A. Lerario, M, "Preoperative Morphine with Postoperative Osteopathic Manipulative Treatment Reduces Patient Analgesic Use After Hysterectomy" JAOA 105 273-279 (2005).

McPhilemy, J.J., Hudanich, R., Hoertz, M., Goldstein, F.J., and Salinsky, J.P., "Osteochondral Autograft Transfer for the Treatment of large Chondral Defects and Osteochondritis Dessicans of the Knee: A Functional Outcome Study" JAmer Osteo Acad of Orthopedics37 62-65 (2000).

Selected Presentations

Pain Management for Chronic Pain Patients”, Compassion and Care National Organization, Philadelphia Meeting, 2014

Pain Treatment For Your Loved Ones” [Presentation for the lay public], Abington Presbyterain Church & Beth Sholom Synagogue, 2014

Clinical Research: Development of an Investigation” Resident Orientation, PCOM, 2014.


"Pennsylvania Study of Chronic Obstructive Pulmonary Exacerbations (PA-SCOPE) Phase 2: Impact of Easy Access to Preventive Care for Impending Acute COPD Exacerbation" Funded by a Pennsylvania Department of Health research grant from the state's share of the national tobacco settlement; Temple University School of Medicine, designated as a Center of Excellence, served as the lead institution.

"Effect of Pre-operative Morphine and Post-op OMT Upon Post-op Pain After Total Abdominal Hysterectomy or Myomectomy." Principal investigator: Goldstein, F.J. Co-Investigators: Berman, M.A., Jeck, S., and Nicholas, A. Funded by the American Osteopathic Association

"Evaluation of the Effect of Selected Osteopathic Manipulative Techniques on Headache Pain: A Randomized Clinical Outcomes Study." Funded by both the American Osteopathic Association and National Headache Foundation

Research Keywords

  • Pain Management
  • Opioid Analgesia
  • Osteopathic Manipulative Treatment (OMT)
Last Updated: 2/25/15