Kerin L. Fresa-Dillon, PhD
Professor of Pathology, Microbiology, Immunology & Forensic Medicine
Department of Bio-Medical Sciences
Dr. Kerin Fresa-Dillon is a professor in the Department of Pathology, Microbiology,
Immunology and Forensic Medicine at PCOM. She earned a PhD in Microbiology and Immunology
from the Medical College of Pennsylvania. She served as a postdoctoral fellow at the
Pennsylvania State University College of Medicine. She joined the College faculty
as an Associate Professor in 1994 and was promoted to Professor in 1999.
Dr. Fresa-Dillon is the Co-Director of the Cellular Molecular Basis of Medicine course,
a multidisciplinary biomedical sciences course taught in the first year of the DO
program. She has also served as PCOM's representative to the Association of American
Medical Colleges Medical School Objectives Program. Dr. Fresa-Dillon is a member of
the American Association of Immunologists, Sigma Xi and the American Association for
the Advancement of Science. Research
"As we age, we become more susceptible to severe illness and death caused by infectious
diseases such as pneumonia, meningitis and blood infections. We are studying a particular
intracellular bacterium called Chlamydophila (Chlamydia) pneumoniae
, which is an important cause of infections of the respiratory system. C. pneumoniae
may also be a cause or aggravating factor for atherosclerosis and Alzheimer's disease,
which mostly affect older people. We have been studying how age affects the severity
and extent of disease caused by C. pneumoniae
in a mouse model. These studies are designed to compare clearance of C. pneumoniae
and the development of disease in young and old mice of two different genetic make-ups.
We will determine if age-related changes in disease caused by C. pneumoniae
are associated with changes in the levels of important molecules, called cytokines,
which are produced by the immune system." Awards
Christian R. and Mary Lindback Award for Distinguished Teaching, PCOM, 2007 Recent publications:
Little, C.S., Bowe, A., Lin, R., Litsky, J., Fogel, R.M., Balin, B.J. and Fresa-Dillon, K.L.
related changes in the extent and severity of C. pneumoniae
infection in Balb/c mice.
Infection and Immunity 73: 1723-1734, 2005. Fresa-Dillon, K.L.,
Cuzzolino, R., and Veit, K.J. Development of a class mission statement as
part of orientation exercises for incoming medical students. JAOA 104
: 251-259, 2004.
Ye, X., Mody, N.S., Hingley, S.T., Coffman, F.D., Cohen, S., and Fresa, K.L.
phosphorylation associated with epipodophyllotoxin-induced apoptosis of lymphoid
Role of a serine/threonine protein kinase. Clin. Immunol. Immunopathol. 89
Sakabe, K., Okuma, M., Kazuno, M., Yamaguchi, T., Yoshida, T., Furuya, H., Kayama,
Suwa, Y., Fujii, W., and Fresa, K.L.
Estrogenic xenobiotics affect the intracellular activation
signal in mitogen-induced human peripheral blood lymphocytes: immunotoxicologic
impact. Int. J. Immunopharm 20
: 205-212, 1998.
Sakabe, K., Okuma, M., Kawashima, I., Kazuno, M., and Fresa, K.L.
Sex hormones affect the
intracellular activation signal in mitogen-stimulated human blood lymphocytes.
Pathophysiology 5: 73-77, 1998.