Farzaneh Daghigh, PhD
Professor of Biochemistry and Molecular Biology
Department of Bio-Medical Sciences
Postdoctoral fellow, DuPont-Merck Pharmaceutical, 1996-1998
PhD, Biochemistry, Temple University, School of Medicine, Department of Biochemistry,
BS, Chemistry, The College of New Jersey, 1988
Dr. Farzaneh Daghigh has served as a Course Director for the Gastroenterological Sciences
course in the DO curriculum. She lectures on biochemistry, metabolism, and nutrition
to the students in the DO and the Biomedical master programs. She participates in
the following courses:
- First Year DO class: Teach in CMBM and Cardiovascular Diseases courses
- Second Year DO: Gastroenterology Course Director; Teach in Life Stages course
- Biomed program: Teach in MBM course
Dr. Daghigh’s current research Projects:
Project 1) Examine the possibility of dietary ω-3 fatty acids, found in fish oil or
oily fish, in diminishing chronic inflammation in human lung fibroblast (HLF) by reducing
nitric oxide. DHA and EPA, ω-3 fatty acids have anti-inflammatory actions that may
benefit asthmatic patients health. Data recently presented at the Pauling Institute,
Project 2) The Nutri One on One Project. The goal of this research study is to improve
patient’s health at the neighboring PCOM clinics. This project is focused to positively
alter patients' knowledge, attitudes, and behaviors about basic nutrition through
one on one coaching in the PCOM affiliated medical clinics. This study was presented
at the Experimental Biology, 2014.
Dr. Daghigh is an advisor for the Nutrition in Medicine Club at the Philadelphia College
of Osteopathic Medicine. She serves this student organization as an educational resource
on nutrition topics important to the PCOM students and community at large.
Farzaneh Daghigh, Ph.D., David Vettori, DO, and Jeffrey Harris, Ph.D. (2011). Nutrition in Medical
Education: History, Current Status, and Resources. Topics in
Clinical Nutrition 26(2) Spring 2011 issue
Book Chapter: (2007) Oxidative Stress: Clinical and Biomedical Implications, Chapter
18, Reactive Oxidant Species and Emerging Therapies in Clinical Medicine. Nova Publishers.
“To Veg or not to Veg”, was the topic of a presentation at the Philadelphia Science
Festival in May 2014. This was a review of the current literature and the state of
biomedical consequences of Vegetarianism and Western diets.
Nutri One-on-One: Improving patients’ Metabolic Profile with One-on-One Nutritional
Coaching. Jennifer King, MS, Jeffrey E. Harris, D.P.H., M.P.H., R.D., David Kuo, DO,
Farzaneh Daghigh, Ph.D., The Experimental Biology Convention, May 2014. San Diego, CA.
Vamsee Duggirala, Donald Hasenmeyer, and Farzaneh Daghigh (2013). Effect of Nicotine and Omega-3 Polyunsatated Fatty acids on Arginine Metabolism
in Asthma. The Linus Pauling Institute Conference, “Diet and Optimum Health”. May,
2013, Corvallis, Oregon.
June 2008-June 2009: Principal Investigator, one year grant for $10,000 funded by
CCDA (the center for Chronic Disease of Aging). This project is titled, “Determination
of the physiologically and pathophysiologicaly relevance of arginase isoforms in NO
production by human gingival fibroblasts”.
2007-2008: Co-Principal Investigator of AOA Grant # 07-10-557 “Documenting Mechanics
and Mechanisms in Pedal Pump OMT” for $22,712.
2006-2007: Co-Principal Investigator of a grant from the Korman’s Foundation for $400,000
titled “Pilot: Gait Analysis, Balance, Nitric Oxide, Fluid Distribution, and Quality-of-Life
of Patients with Parkinson’s Disease (PD) treated with Whole Body, Periodic Acceleration
or Osteopathic Manipulative Treatment (OMT)”.
October 2003: Co-Principal Investigator of a grant from the Karen and Herbert Lotman
Foundation for $25,000 titled “A pilot study to establish a protocol to determine
the change in nitric oxide (NO) concentrations after treatment with the Accelerated
Therapeutic 101 (AT101) table in normal healthy subjects and patient volunteers”.
Media Dr. Daghigh discussed the costs and benefits of a vegetarian diet. The Philadelphia Inquirer, Nov. 9, 2014
Dr. Daghigh discussed the health ramifications of a vegetarian diet at Franklin Institute's
program "To Veg or Not to Veg.", May 30, 2014
Dr. Daghigh Weighs in on Diet Cookies, Farzaneh Daghigh, PhD, professor, biochemistry/molecular
biology, was tapped by Channel Six to weigh in on the ingredients of a popular diet
cookie. Video on PCOM’s Facebook page, October 7, 2009
- Nitric oxide
- Arginine metabolism
- Nutritional education
- Nutritional intervention