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Medicine & Cancer Therapy

  

Personalized Medicine and Cancer Therapy

Saturday, May 15, 2010

Evans Hall - Room 334 A/B
4170 City Avenue
Philadelphia, PA

Hossein Borghaei, DO, MS
Program Chairman

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Description
Cancer therapy is heading in a new and exciting direction. The discovery of various pathways that control cancer growth and metastasis has led to the identification of key genes and proteins. Specific inhibitors of these important intermediaries are now in clinical practice with promising results. By directly targeting the cancer cells, many of the unwanted side effects of traditional chemotherapies can now be avoided. These findings have also opened the way for examining each patient's tumor and directing therapy based on the molecular make up of the tumor. We will review some of the most recent findings in select tumors that allow for individualization of therapy and examine the role of cancer biomarkers and genetic testing inpatients diagnosed with malignancies.

Objective

At the conclusion of this presentation, the participant will be able to:

  • Understand the difference between predictive biomarker and a prognostic biomarker.
  • Recognize how different molecular signals are changing the treatment of different cancers (like breast, colon and lung).
  • Enhance knowledge and awareness of common cancer syndromes.
  • Understand basic criteria for cancer risk assessment referral.
  • Highlight pitfalls in commercial genetic test imterpretation and stress the importance of genetic counseling.
  • Define risk categories for patients with localized prostate cancer.
  • Review treatment options for patients with prostate cancer.
  • Discuss risks and benefits for androgen deprivation therapy.
  • Understand the impact of histology.
  • Recognize the role of molecular testing of tumors and increase knowledge of targeted therapies.
  • Understand the benefits and shortcomings of tumor markers.
  • Understand the rationale behind the use of newer targeted agents and the potential benefits of newer agents over standard therapy.
  • Understand the potential problems with these agents (financial and medical).

Schedule

7:30 a.m. Registration & Continental Breakfast
7:45 a.m. Welcome and Introduction
Hossein Borghaei, DO, MS, Assistant Professor, Department of Medical Oncology, Director of Lung, Head and Neck Cancer Risk Assessment Program, Fox Chase Cancer Center
8:00 a.m. Biomarkers
Eric Sbar, DO, Director, Global Clinical Development, Bristol-Myers Squibb
8:45 a.m. Overview of Genetic Testing for Cancer Risk Assessment
Michael Hall, MD, Assistant Professor, Departments of Clinical Genetics and Medical Oncology, Director, Gastrointestinal Risk Assessment, Fox Chase Cancer Center
9:30 a.m. The Role of the Primary Care Physician in Patients' Prostate Cancer Treatment Decision Making
Yu-Ning Wong, MD, Assistant Professor, Department of Medical Oncology and Population Science, Fox Chase Cancer Center
10:15 a.m. Break
10:30 a.m. Personalized Lung Cancer Treatment
Hossein Borghaei, DO, MS
11:30 a.m. GYN Oncology
Rocco J. Crescenzo, DO, FACOI, Assistant Professor, Department of Internal Medicine, Chairman, Division of Hematology and Oncology, Philadelphia College of Osteopathic Medicine; Medical Director, Oncology Research and Development, GlaxoSmithKline
12:15 - 1:00 p.m. Panel Discussion / Adjourn

Continuing Education Credit
"The Philadelphia College of Osteopathic Medicine has requested that the AOA Council on Continuing Medical Education approve this program for five hours of AOA Category 1-A CME credits. Approval is currently pending." Sign-in and full day attendance of program is required for credit. All faculty participating in continuing medical education programs sponsored by PCOM are expected to disclose to the program audience whether they do or do not have any real or apparent conflict(s) of interest or other relationships related to the content of their presentation(s).

Parking
On-campus parking is available in our garage, please enter on Stout Road. All-day parking is $5.00. Please note: the automated gate takes quarters or one, five and ten dollar bills. Enter Evans Hall through the front entrance across from the parking garage.

Fee Policies
Physicians $125.00, Physician Assistants and other Health Care Professionals, $75.00. Registration fees for Saturday and Sunday programs are not refundable, nor can they be credited to future programs.

Emergency Messages
Call PCOM Rowland Hall Security Desk at (215) 871-6351 ask the guard to transfer your call to ext. 5350 which is the phone in Evans Hall.